[Swallowing after chemotherapy and radiotherapy for laryngeal and hypopharyngeal carcinomas]

  • Cintra A
  • Vale L
  • Feher O
 et al. 
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The main goals of the larynx preservation protocol are eradication of cancer and preservation of a functional larynx with maintenance of respiration, phonation and swallowing. Few studies, however have addressed functional outcomes. OBJECTIVE: Functional evaluation of oropharyngeal swallowing in patients enrolled in a larynx preservation protocol at the Hospital do Cancer AC Camargo. METHODS: Evaluation of swallowing was performed by videofluoroscopy in 31 patients, focusing on: oropharyngeal motility disorders, stasis, laryngeal penetration, aspiration and severity of dysphagia. RESULTS: Swallowing analysis: 5 patients showed inefficient bolus preparation, 14 had changes in the bolus propulsion; 23 patients had a reduced laryngeal elevation, 26 presented with stasis in the vallecula and 14 with stasis in hypopharynx. Nine patients presented silent aspiration. We detected functional swallowing in 11 patients; mild dysphagia in 7; mild/moderate in 7; moderate in 3 and severe dysphagia in 3. CONCLUSION: Larynx preservation results in changes of swallowing, ranging in their majority from discrete to moderate. Some patients, however, developed severe dysphagia, and oral feeding was not possible.

Author-supplied keywords

  • Adult
  • Aged
  • Antineoplastic Agents/therapeutic use
  • Carcinoma, Squamous Cell/drug therapy/*physiopatho
  • Cisplatin/therapeutic use
  • Combined Modality Therapy
  • Deglutition Disorders/etiology/*physiopathology
  • Dyspepsia/etiology
  • Female
  • Fluoroscopy
  • Humans
  • Hypopharyngeal Neoplasms/complications/drug
  • Laryngeal Neoplasms/drug therapy/*physiopathology/
  • Male
  • Middle Aged
  • Paclitaxel/analogs & derivatives/therapeutic use
  • Severity of Illness Index
  • Treatment Outcome
  • Video Recording
  • therapy/*physiopathology/radiotherapy

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  • A B Cintra

  • L P Vale

  • O Feher

  • I N Nishimoto

  • L P Kowalski

  • E C Angelis

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