(Chemical Equation Presented) Syntheses of spirocyclic bis-1,2-dioxolanes, bis-1,2-dioxanes, and bis-1,2-dioxepanes are achieved through intramolecular ketalizations of hydroperoxy ketones or intramolecular alkylations of gem-dihydroperoxides. The spiroperoxides have excellent thermal and chemical stability, and several display promising activity against P. falciparum. © 2008 American Chemical Society.
CITATION STYLE
Ghorai, P., Dussault, P. H., & Hu, C. (2008). Synthesis of spiro-bisperoxyketals. Organic Letters, 10(12), 2401–2404. https://doi.org/10.1021/ol800657m
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