Systemic cytokine response to three bouts of eccentric exercise

  • Cornish S
  • Johnson S
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Abstract

This research examined the changes in inflammatory cytokines interleukin 6 (IL-6), IL-1β, IL-10, as well as muscle force, muscle soreness, thigh circumference, and range of motion in response to 3 bouts of eccentric knee extension. Ten males were recruited to participate. The participants performed eccentric exercise on 3 consecutive days on the knee extensors on the right leg separated by 24 h. Participants performed 6 sets of 10 repetitions of isokinetic eccentric knee extension at 120° per second. Blood was sampled before and after each exercise bout and 24 h after the final exercise bout. Muscle isometric force, delayed onset muscle soreness (DOMS), thigh circumference, and range of motion were evaluated before and after each exercise bout and 24 h after the final exercise bout. There were no statistically significant differences noted for the changes in isometric strength, thigh circumference, and range of motion, or IL-6 over the 4days (all p>0.05). On the second day and third day there was a significant increase noted in DOMS as compared with baseline (p

Author-supplied keywords

  • Delayed onset muscle soreness
  • Eccentric exercise
  • Inflammation
  • Interleukin 6

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