T regulatory cells and allergy

  • Taylor A
  • Verhagen J
  • Akdis C
 et al. 
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Abstract

Anergy, tolerance and active suppression may not be independent events, but rather involve similar mechanisms and cell types in immune regulation. Induction of allergen-specific TRegcells seems essential for maintaining a healthy immune response towards allergens. By utilizing multiple secreted cytokines and surface molecules, antigen-specific TRegcells may re-direct an inappropriate immune response against allergens or auto-antigens. © 2005 Elsevier SAS. All rights reserved.

Author-supplied keywords

  • Anergy
  • IgE
  • Immunotherapy
  • T cells
  • T regulatory cells
  • Tolerance

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