Temporary placement of covered self-expandable metal stents in benign biliary strictures: a new paradigm? (with video)

  • Kahaleh M
  • Behm B
  • Clarke B
 et al. 
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Abstract

Background: Benign biliary strictures (BBS) are usually managed with plastic stents, whereas placement of uncovered metallic stents has been associated with failure related to mucosal hyperplasia. Objective: We analyzed the efficacy and safety of temporary placement of a covered self-expanding metal stent (CSEMS) in BBS. Design: Patients with BBS received temporary placement of CSEMSs until adequate drainage was achieved; confirmed by resolution of symptoms, normalization of liver function tests, and imaging. Setting: Tertiary-care center with long-standing experience with CSEMSs. Patients: Seventy-nine patients with BBS secondary to chronic pancreatitis (32), calculi (24), liver transplant (16), postoperative biliary repair (3), autoimmune pancreatitis (3), and primary sclerosing cholangitis (1). Intervention: ERCP with temporary CSEMS placement. Removal of CSEMSs was performed with a snare or a rat-tooth forceps. Main Outcome Measurements: End points were efficacy, morbidity, and clinical response. Results: CSEMSs were removed from 65 patients. Resolution of the BBS was confirmed in 59 of 65 patients (90%) after a median follow-up of 12 months after removal (range 3-26 months). If patients who were lost to follow-up, developed cancer, or expired were considered failures, then an intent-to-treat global success rate of 59 of 79 (75%) was obtained. Complications associated with placement included 3 post-ERCP pancreatitis (4%), 1 postsphincterotomy bleed (1%), and 2 pain that required CSEMS removal (2%). In 11 patients (14%), the CSEMS migrated. In 1 patient, CSEMS removal was complicated by a bile leak that was successfully managed with plastic stents. Limitation: Pilot study from a single center. Conclusions: Temporary CSEMS placement in patients with BBS offers a potential alternative to surgery. © 2008 American Society for Gastrointestinal Endoscopy.

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Authors

  • Michel KahalehNewYork Presbyterian Hospital-Weil Cornell Medical Center

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  • Brian Behm

  • Bridger W. Clarke

  • Andrew Brock

  • Vanessa M. Shami

  • Sarah A. De La Rue

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