Therapeutic use of coenzyme Q10 and coenzyme Q10-related compounds and formulations.

  • Villalba J
  • Parrado C
  • Santos-Gonzalez M
 et al. 
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Abstract

Coenzyme Q(10) (CoQ(10)) is found in blood and in all organs. CoQ(10) deficiencies are due to autosomal recessive mutations, ageing-related oxidative stress and carcinogenesis processes, and also statin treatment. Many neurodegenerative disorders, diabetes, cancer and muscular and cardiovascular diseases have been associated with low CoQ(10) levels, as well as different ataxias and encephalomyopathies.

Author-supplied keywords

  • Animals
  • Cardiovascular Diseases
  • Cardiovascular Diseases: drug therapy
  • Cardiovascular Diseases: enzymology
  • Cardiovascular Diseases: genetics
  • Chemistry, Pharmaceutical
  • Chemistry, Pharmaceutical: methods
  • Humans
  • Neurodegenerative Diseases
  • Neurodegenerative Diseases: drug therapy
  • Neurodegenerative Diseases: enzymology
  • Neurodegenerative Diseases: genetics
  • Ubiquinone
  • Ubiquinone: chemistry
  • Ubiquinone: deficiency
  • Ubiquinone: therapeutic use

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Authors

  • Jose M Villalba

  • Cristina Parrado

  • Monica Santos-Gonzalez

  • Francisco J Alcain

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