Thinking about genetic redundancy

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Abstract

Partial functional redundancy among genes is frequently observed in a wide range of organisms and processes, but the selective value of such redundancy is not immediately apparent. Any fully redundant function should be evolutionarily unstable: unless selection acts to maintain the redundancy it will tend to be lost by mutational drift. I discuss four possible mechanisms by which selection might act to maintain genetic redundancy. © 1993.

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Thomas, J. H. (1993). Thinking about genetic redundancy. Trends in Genetics. https://doi.org/10.1016/0168-9525(93)90140-D

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