Three new glutarimide alkaloids from Croton cuneatus

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Abstract

Analysis of the dichloromethane extract of the aerial parts of Croton cuneatus led to the isolation of the new glutarimide alkaloids: julocrotol (1), isojulocrotol (2), and julocrotone (3) along with the known compounds julocrotonine (4), lichexanthone (5) and selin-11-en-4α-ol (6). The structures of the new compounds were established by spectral methods. The in vitro cytotoxic activity of Compounds 1-6 was evaluated against six human tumor cells lines. © 2004 Taylor & Francis Ltd.

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Suárez, A. I., Blanco, Z., Delle Monache, F., Compagnone, R. S., & Arvelo, F. (2004). Three new glutarimide alkaloids from Croton cuneatus. Natural Product Research, 18(5), 421–426. https://doi.org/10.1080/14786410310001622004

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