Toxin A-negative, toxin B-positive Clostridium difficile

  • Drudy D
  • Fanning S
  • Kyne L
  • 100

    Readers

    Mendeley users who have this article in their library.
  • 103

    Citations

    Citations of this article.

Abstract

Clostridium difficile is a major cause of infectious diarrhea in hospitalized patients. Many pathogenic strains of Clostridium difficile produce two toxins TcdA and TcdB, both of which are pro-inflammatory and enterotoxic in human intestine. Clinically relevant toxin A-negative, toxin B-positive (A-B+) strains of Clostridium difficile that cause diarrhea and colitis in humans have been isolated with increasing frequency worldwide. This perspective describes these important toxin variant strains and highlights the need to use Clostridium difficile diagnostic methods that can detect both TcdA and TcdB. © 2006 International Society for Infectious Diseases.

Author-supplied keywords

  • A-B+Clostridium difficile
  • Bacterial genotyping
  • Infectious diarrhea

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free