Transient increase of NMDA-binding sites in human hippocampus during development

  • Represa A
  • Tremblay E
  • Ben-Ari Y
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Abstract

In the human hippocampus, the density of glutamate and N-methyl-d-aspartate (NMDA) binding sites follows during development a bell-shaped curve with a peak at 23-27 fetal weeks. We suggest that there is a transient increased density of NMDA binding sites during a restricted period of hippocampal development; this may play an important role in developmental plasticity. © 1989.

Author-supplied keywords

  • Autoradiography
  • Development
  • Glutamate
  • Human hippocampus
  • N-Methyl-d-aspartate

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