Treating to target: A strategy to cure gout

  • Perez-Ruiz F
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Abstract

Acute gout attacks and the long-term complications of gout are associated with the deposition of monosodium urate (MSU) monohydrate crystals in the joints and soft tissues, causing acute and chronic inflammation. The aim of long-term treatment is to reduce the serum urate (sUA) level to 6 mg/dl (⩽360 μmol/l), below the saturation point of MSU, so that new crystals cannot form and existing crystals are dissolved. Serial joint aspiration studies confirmed the disappearance of crystals with effective urate-lowering therapy. There is good evidence that achieving sUA

Author-supplied keywords

  • Arthrocentesis
  • Crystals
  • Cure
  • Gout
  • Monosodium urate
  • Tophi
  • Treatment target
  • Urate-lowering

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