Treatment with agalsidase beta during pregnancy in Fabry disease

  • Politei J
  • 19


    Mendeley users who have this article in their library.
  • 12


    Citations of this article.


Fabry disease is an X-linked lysosomal storage disease caused by a deficiency of alpha-galactosidase A, which leads to excessive accumulation of glycosphingolipids in most tissues in the body, with life-threatening clinical consequences in the kidney, heart, and cerebrovascular system. Enzyme replacement therapy using exogenously produced alpha-galactosidase has been available for treatment of this multisystem progressive disease since 2001. Two different preparations of enzyme replacement therapy for Fabry disease are available outside of the USA: agalsidase alfa and agalsidase beta. Despite being X-linked, Fabry disease affects many female patients, and this report presents a successful pregnancy of a female patient receiving agalsidase beta.

Author-supplied keywords

  • Agalsidase beta
  • Fabry disease
  • Pregnancy

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Juan M. Politei

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free