Unexpected severe calcification after transplantation of bone marrow cells in acute myocardial infarction.

  • Yoon Y
  • Park J
  • Tkebuchava T
 et al. 
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Abstract

There has been a rapid increase in the number of clinical trials using unselected bone marrow (BM) cells or the mononuclear fraction of BM cells for treating ischemic heart diseases. Thus far, no significant deleterious effects or complications have been reported in any studies using BM-derived cells for treatment of various cardiac diseases.

Author-supplied keywords

  • Animals
  • Bone Marrow Transplantation
  • Bone Marrow Transplantation: adverse effects
  • Calcinosis
  • Calcinosis: etiology
  • Calcinosis: pathology
  • Cardiomyopathies
  • Cardiomyopathies: etiology
  • Cardiomyopathies: pathology
  • Cell Differentiation
  • Cells
  • Clone Cells
  • Clone Cells: transplantation
  • Cultured
  • Cultured: transplantation
  • Female
  • Inbred F344
  • Male
  • Multipotent Stem Cells
  • Multipotent Stem Cells: pathology
  • Multipotent Stem Cells: transplantation
  • Myocardial Infarction
  • Myocardial Infarction: pathology
  • Myocardial Infarction: surgery
  • Myocardial Infarction: ultrasonography
  • Postoperative Complications
  • Postoperative Complications: etiology
  • Postoperative Complications: pathology
  • Random Allocation
  • Rats

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Authors

  • Young-Sup Yoon

  • Jong-Seon Park

  • Tengiz Tkebuchava

  • Corinne Luedeman

  • Douglas W Losordo

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