Upregulation of UCP2 by adiponectin: The involvement of mitochondrial superoxide and hnRNP K

  • Zhou M
  • Xu A
  • Tam P
 et al. 
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Abstract

The adipocyte-derived hormone adiponectin elicits protective functions against fatty liver diseases and hepatic injuries at least in part by stimulating the expression of a mitochondrial inner membrane transporter, uncoupling protein 2 (UCP2). The present study was designed to investigate the cellular and molecular mechanisms underlying adiponectin-induced UCP2 expression.

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