This study sought to assess the safety of cardiopulmonary stress testing in 40 children with pulmonary arterial hypertension and to compare exercise responses in this patient cohort with those of a healthy control population. Patients with pulmonary hypertension had significant impairment in aerobic capacity, with a peak oxygen consumption of 20.7 ± 6.9 versus 35.5 ± 7.4 ml/kg/min in healthy controls (p <0.0001). Peak oxygen consumption was strongly correlated with invasive measures of disease severity, including pulmonary vascular resistance index (r = -0.6, p = 0.006). Exercise testing can be performed safely in this group of patients and can yield valuable clinical information. © 2005 Excerpta Medica Inc.
CITATION STYLE
Yetman, A. T., Taylor, A. L., Doran, A., & Ivy, D. D. (2005). Utility of cardiopulmonary stress testing in assessing disease severity in children with pulmonary arterial hypertension. American Journal of Cardiology, 95(5), 697–699. https://doi.org/10.1016/j.amjcard.2004.10.056
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