Vaccine innovation: Lessons from World War II

  • Hoyt K
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Abstract

World War II marked a watershed in the history of vaccine development as the military, in collaboration with academia and industry, achieved unprecedented levels of innovation in response to war-enhanced disease threats such as influenza and pneumococcal pneumonia. In the 1940s alone, wartime programs contributed to the development of new or significantly improved vaccines for 10 of the 28 vaccine-preventable diseases identified in the 20th century. This article examines the historical significance of military organizations and national security concerns for vaccine development in the United States. © 2006 Palgrave Macmillan Ltd.

Author-supplied keywords

  • Biodefense
  • Health Knowledge, Attitudes, Practice
  • History, 20th Century
  • Humans
  • Innovation
  • Japanese encephalitis vaccine
  • Military
  • Military Medicine
  • Pneumococcus polysaccharide
  • Pneumococcus vaccine
  • United States
  • Vaccine
  • Vaccines
  • World War II
  • anthrax
  • anthrax vaccine
  • army
  • article
  • attitude to health
  • biological warfare
  • botulinum toxin
  • cholera
  • cholera vaccine
  • clinical trial
  • drug efficacy
  • drug hypersensitivity
  • drug treatment failure
  • epidemic encephalitis
  • government
  • history
  • human
  • immunology
  • infection
  • infection prevention
  • influenza
  • influenza vaccine
  • insect repellent
  • lobar pneumonia
  • military medicine
  • nonhuman
  • organization
  • penicillin G
  • plague
  • plague vaccine
  • review
  • smallpox
  • smallpox vaccine
  • sulfapyridine
  • sulfonamide
  • tetanus
  • tetanus toxoid
  • threat
  • typhoid fever
  • typhoid vaccine
  • typhus vaccine
  • vaccination reaction
  • vaccine
  • vaccine production
  • war
  • yellow fever
  • yellow fever vaccine

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Authors

  • K Hoyt

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