Vertebral artery origin stenosis (VAOS) is a common but underappreciated cause of stroke. It causes as many as 20% of posterior circulation stroke. This article reviews the epidemiology, natural history, and treatment of this condition. We focus on the emerging therapeutic endovascular options and their safety and durability. Finally, we discuss the gaps in the current understanding of VAOS and how best to explore them in the future. © 2011 by National Stroke Association.
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