Virtual reality-induced cortical reorganization and associated locomotor recovery in chronic stroke: an experimenter-blind randomized study [corrected] [published erratum appears in STROKE 2005 Jul;36(7):1625].

  • SH Y
  • SH J
  • Kim Y
 et al. 
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Abstract

Background and Purpose--Virtual reality (VR) is a new promising computer-assisted technology to promote motor recovery in stroke patients. VR-induced neuroplasticity supporting locomotor recovery is not known. We investigated the effects of VR intervention on cortical reorganization and associated locomotor recovery in stroke patients.Methods--Ten chronic stroke patients were assigned randomly to either the control group or the VR group. VR was designed to provide interactive real-life practice environments in which practice parameters can be individualized to optimize motor relearning. Laterality index (LI) in the regions of interests (ROIs) and locomotor recovery were measured before and after VR using functional MRI (fMRI) and standardized locomotor tests, respectively. The t test and nonparametric test were performed to compare the mean differences at P0.05). Motor function was significantly improved after VR (P

Author-supplied keywords

  • Adult
  • Brain -- Physiology
  • Clinical Assessment Tools
  • Clinical Trials
  • Data Analysis Software
  • Female
  • Funding Source
  • Human
  • Intraclass Correlation Coefficient
  • Locomotion
  • Magnetic Resonance Imaging -- Methods
  • Male
  • Mann-Whitney U Test
  • Middle Age
  • Recovery
  • Scales
  • Single-Blind Studies
  • Stroke -- Rehabilitation
  • T-Tests
  • Test-Retest Reliability
  • Virtual Reality
  • Wilcoxon Rank Sum Test

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Authors

  • You SH

  • Jang SH

  • Y Kim

  • M Hallett

  • Ahn SH

  • Y Kwon

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