White matter development during late adolescence in healthy males: a cross-sectional diffusion tensor imaging study

  • Ashtari M
  • Cervellione K
  • Hasan K
 et al. 
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Abstract

BACKGROUND: Previous MRI studies of healthy children have reported age-related white matter (WM) changes in language and motor areas of the brain. The authors investigated WM development in healthy adolescent males through age-associated changes in fractional anisotropy (FA), radial (lambda( perpendicular)) and axial (lambda(||)) diffusivity. METHODS: Twenty-four healthy adolescent males (mean age=16.6, SD=2.5 years) were divided into two groups with an age split of 16.9 years and underwent a whole-brain voxelwise analysis. RESULTS: At a threshold of p

Author-supplied keywords

  • *Diffusion Magnetic Resonance Imaging
  • Adolescent
  • Adult
  • Brain/*anatomy & histology/*growth & development
  • Child
  • Humans
  • Male
  • Reference Values

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Authors

  • M Ashtari

  • K L Cervellione

  • K M Hasan

  • J Wu

  • C McIlree

  • H Kester

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