Work absences and expenditures for employees with autoimmune inflammatory diseases

  • Nair K
  • Naim A
  • Draaghtel K
 et al. 
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OBJECTIVE: Economic burden was compared for employees with autoimmune inflammatory diseases (AutoIDs) who received anti-tumor necrosis factor (TNF) α agents, those who did not, and those with no AutoID.

METHODS: Retrospective claims data analysis (2000-2006). Propensity analysis created two groups: (1) adult AutoID patients with anti-TNFα therapy (AutoID/anti-TNFα) matched to those with no anti-TNFα therapy (AutoID/non-anti-TNFα), and (2) non-AutoID patients (control) matched to all AutoID patients (AutoID). Indirect, direct, and total expenditures after controlling for various covariates were compared using regression analysis.

RESULTS: Total direct and total expenditures were, respectively, $13,187 and $13,373 higher for AutoID/anti-TNFα group (n = 689) versus AutoID/non-anti-TNFα group (n = 2699). Indirect expenditures were not statistically different between the groups. AutoID- (n = 12,612) and control-group (n = 48,895) differences showed similar trends.

CONCLUSIONS: These results provide useful information to employers about the cost burden associated with AutoIDs.

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  • Kavita V. Nair

  • Ahmad B. Naim

  • Ksenia Draaghtel

  • Jill Van Den Bos

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