Yeast expression platforms

  • Böer E
  • Steinborn G
  • Kunze G
 et al. 
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Abstract

Yeasts provide attractive expression platforms. They combine ease of genetic manipulations and the option for a simple fermentation design of a microbial organism with the capabilities of an eukaryotic organism to secrete and to modify a protein according to a general eukaryotic scheme. For platform applications, a range of yeast species has been developed during the last decades. We present in the following review a selection of established and newly defined expression systems. The review is concluded by the description of a wide-range vector system that allows the assessment of the selected organisms in parallel for criteria like secretion or appropriate processing and modification in a given case.

Author-supplied keywords

  • Heterologous gene expression
  • Transformation
  • Wide-range vector system
  • Yeast expression platforms

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