Several chiral octahedral complexes of the general formula [Ru(bpy) 2(Lig)][PF6]2 (Lig = a ligand that can participate in π-stacking interactions such as eilatin, isoeilatin, and tpphz) were synthesized in both the racemic and enantiomerically pure/enriched forms. Nonracemic mixtures of enantiomers of all these complexes exhibit splitting of the 1H NMR spectra (NMR nonequivalence); i.e., each spectrum contains a major and a minor set of peaks. The origin of this phenomenon is attributed to a fast equilibrium between monomers and discrete dimers held together by π-stacking interactions, and it is observed for a wide range of π-stacking interaction strengths. The NMR spectrum splitting exhibited by these complexes can be exploited for the evaluation of their enantiomeric excess simply from the integral ratio, without addition of chiral shift reagents. © 2005 American Chemical Society.
CITATION STYLE
Bergman, S. D., & Kol, M. (2005). π-Stacking induced NMR spectrum splitting in enantiomerically enriched Ru(II) complexes: Evaluation of enantiomeric excess. Inorganic Chemistry, 44(6), 1647–1654. https://doi.org/10.1021/ic048569e
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