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Bioactive compounds from marine bacteria and fungi.

by Abdessamad Debbab, Amal H Aly, Wen H Lin, Peter Proksch
Section Title: Microbial, Algal, and Fungal Biochemistry ()
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A review. Marine bacteria and fungi are of considerable importance as new promising sources of a huge no. of biol. active products. Some of these marine species live in a stressful habitat, under cold, lightless and high pressure conditions. Surprisingly, a large no. of species with high diversity survive under such conditions and produce fascinating and structurally complex natural products. Up till now, only a small no. of microorganisms have been investigated for bioactive metabolites, yet a huge no. of active substances with some of them featuring unique structural skeletons have been isolated. This review covers new biol. active natural products published recently (2007-09) and highlights the chem. potential of marine microorganisms, with focus on bioactive products as well as on their mechanisms of action. [on SciFinder(R)]

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