Abstract
Water-dispersed colloidal gold nanoparticles (AuNPs) with high concentration were synthesized from metal precursor HAuCl4. The bovine serum albumin (BSA) and heterobiofunctionalized thiol polyethylene glycol acid (HS-PEG-COOH) were used as biofunctionalized layers for the synthesized AuNPs. The BSA and HS-PEG-COOH bound to the AuNPs were characterized qualitatively and quantitatively by transmission electron microscope and UV-VS spectrophotometer. The fabricated BSA and HS-PEG-COOH-capped AuNPs were introduced in mouse to study its toxicity and its availability in the liver. © 2012 Vietnam Academy of Science & Technology.
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Nghiem, T. H. L., Nguyen, T. T., Fort, E., Nguyen, T. P., Hoang, T. M. N., Nguyen, T. Q., & Tran, H. N. (2012). Capping and in vivo toxicity studies of gold nanoparticles. Advances in Natural Sciences: Nanoscience and Nanotechnology, 3(1). https://doi.org/10.1088/2043-6262/3/1/015002
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