Bioassay directed isolation of the EtOAc extract from a traditional Chinese medicine Psoralea corylifolia resulted in the purification of two isoflavonoids, corylifols D (1) and E (2), along with four known ones. The structures of 1 and 2 were determined by extensive 1D and 2D NMR and MS data analyses. When tested against HepG2 and Hep3B hepatocellular carcinoma cell lines, corylifol A (4) displayed IC50 values of 4.6 and 13.5 μg/ml, respectively. © 2013 Copyright Taylor and Francis Group, LLC.
CITATION STYLE
Song, P., Yang, X. Z., & Yuan, J. Q. (2013). Cytotoxic constituents from Psoralea corylifolia. Journal of Asian Natural Products Research, 15(6), 624–630. https://doi.org/10.1080/10286020.2013.793181
Mendeley helps you to discover research relevant for your work.