Genetics of Briquet's syndrome and somatization disorder: A review of family, adoption, and twin studies.

by Samuel B Guze
Annals of Clinical Psychiatry ()


Reviews publications in English that dealt with either Briquet's syndrome or Diagnostic and Statistical Manual of Mental Disorders-III (DSM-III) and DSM-III-Revised (DSM-III-R) somatization disorder. Results provide significant evidence that Briquet's syndrome runs in families, primarily among female relatives, and is associated in the same individual and in 1st-degree relatives with diagnoses of antisocial personality and/or alcoholism. While there is considerable overlap in individuals diagnosed with Briquet's syndrome or somatization disorder, there remains a significant discordance in the diagnoses. The occurrence of Briquet's syndrome and antisocial personality in adulthood seems to be associated with childhood hyperactivity. Thorough diagnostic examinations should include a detailed present illness and extensive past medical history, including significant illnesses, hospitalizations, visits to the emergency room, surgeries, and injuries. (PsycINFO Database Record (c) 2012 APA, all rights reserved)

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