The improved synthesis of Jacobsen catalyst 1 was developed. For both enantiomers the obtained overall yield starting from commercially available 4 was 80-85%.
CITATION STYLE
Cepanec, I., Mikuldaš, H., & Vinković, V. (2001). An improved method for synthesis of Jacobsen’s catalyst. Synthetic Communications, 31(19), 2913–2919. https://doi.org/10.1081/SCC-100105661
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