An efficient and simple method for the oxidative coupling of benzylic and allylic sp3 C-H bonds with active methylenic sp3 C-H bonds under metal-free conditions was developed by employing 2,3-dichloro-5,6- dicyanobenzoquinone (DDQ) as an oxidant. The reaction was shown to proceed smoothly for various 1,3-dicarbonyl compounds with a range of benzylic and allylic substrates in good to excellent yields. © 2010 Elsevier Ltd. All rights reserved.
CITATION STYLE
Ramesh, D., Ramulu, U., Rajaram, S., Prabhakar, P., & Venkateswarlu, Y. (2010). Metal-free oxidative C-C bond formation of active methylenic sp3 C-H bonds with benzylic sp3 C-H and allylic sp3 C-H bonds mediated by DDQ. Tetrahedron Letters, 51(37), 4898–4903. https://doi.org/10.1016/j.tetlet.2010.07.080
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