Skip to content

Microparticles used as drug delivery systems

by Juergen Siepmann, Florence Siepmann
Progress in Colloid and Polymer Science ()
Get full text at journal


Microparticles offer various significant advantages as drug delivery systems, including: (i) an effective protection of the encapsulated active agent against (e.g. enzymatic) degradation, (ii) the possibility to accurately control the release rate of the incorporated drug over periods of hours to months, and (iii) an easy administration (compared to alternative parenteral controlled release dosage forms, such as macro-sized implants). Desired, pre-programmed drug release profiles can be provided which match the therapeutic needs of the patient. This article gives an overview on the most important past, current and future strategies using drug-loaded microparticles to improve the efficiency of various medical treatments. Special emphasis is laid on the different types of preparation techniques that are commonly used, the physicochemical properties of the devices and practical examples illustrating the considerable benefits of this type of advanced drug delivery systems. But also the major challenges and obstacles to be overcome during the development and production of these pharmaceutical dosage forms are pointed out.

Cite this document (BETA)

Readership Statistics

10 Readers on Mendeley
by Discipline
30% Chemistry
20% Agricultural and Biological Sciences
20% Engineering
by Academic Status
40% Researcher
40% Student > Master
10% Other
by Country
10% Spain

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Sign up & Download

Already have an account? Sign in