A retrospective study was made of 38 myosarcomas of the small and large intestines (34 leiomyosarcomas and 4 malignant leiomyoblastomas). Endoenteric, small, and noninvasive tumors were successfully treated by simple wedge excision, cautery snare removal, or segmental bowel resection with a high 5‐yr cure rate of 86% (12/14). Exo‐enteric tumors often invaded adjacent structures or perforated into the peritoneal cavity. Extensive resection procedures, including pancreaticoduodenectomy, abdominoperineal resection, and pelvic exenteration salvaged only 13% (2/16) of these patients. Three clinicopathologic factors adversely affected prognosis: i(tumor size greater than 5 cm in diameter, ii) extra‐intestinal invasion or free perforation, and iii high histopathologic grade of malignancy. The presence of none, one, two, or three of these adverse factors gave decreasing 5‐yr survival rates of 100, 44, 31, and 0%, respectively. These observations suggest use of a multimodal treatment program that may minimize treatment failure from local as well as distant disease. Copyright © 1983 Wiley‐Liss, Inc., A Wiley Company
CITATION STYLE
Shiu, M. H., Farr, G. H., Egeli, R. A., Quan, S. H. G., & Hajdu, S. I. (1983). Myosarcomas of the small and large intestine: A clinicopathologic study. Journal of Surgical Oncology, 24(1), 67–72. https://doi.org/10.1002/jso.2930240116
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