Skip to content

Neurosedative and muscle relaxant activities of aqueous extract of Bryophyllum pinnatum

by O. K. Yemitan, H. M. Salahdeen
Fitoterapia ()
Get full text at journal


The saline leaf extract of Bryophyllum pinnatum was investigated on neuropharmacological activities to ascertain claims of local use. When tested in mice, it produced a dose-dependent prolongation of onset and duration of pentobarbitone-induced hypnosis, reduction of exploratory activities in the head-dip and evasion tests. Moreover, a dose-dependent muscle in-coordination was observed in the inclined screen, traction and climbing tests. It delayed onset to convulsion in both strychnine- and picrotoxin-induced seizures in addition to minimal protection against picrotoxin seizures. ?? 2005 Elsevier B.V. All rights reserved.

Cite this document (BETA)

Readership Statistics

12 Readers on Mendeley
by Discipline
58% Medicine and Dentistry
17% Chemistry
8% Pharmacology, Toxicology and Pharmaceutical Science
by Academic Status
33% Student > Ph. D. Student
17% Student > Postgraduate
17% Student > Bachelor
by Country
8% India

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Sign up & Download

Already have an account? Sign in