Transcriptomics and Proteomics: Integration?

  • Ludvigsen M
  • Honoré B
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Abstract

The genes are transcribed to pre-messenger RNA, further processed to messenger RNA (transcripts), and finally translated into protein. The transcriptome constitutes the complete set of different transcripts that is synthesized in the lifetime of a cell or a tissue. The proteome refers to the complete set of proteins that is expressed, and modified following expression in the lifetime of a cell or a given tissue. Transcriptomics refers to the study of the transcriptome, while proteomics refers to the study of the proteome using large-scale technologies for transcript or protein analyses. The two disciplines each provide unique information and supplement each other.

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Ludvigsen, M., & Honoré, B. (2018). Transcriptomics and Proteomics: Integration? In Encyclopedia of Life Sciences (pp. 1–7). Wiley. https://doi.org/10.1002/9780470015902.a0006188.pub2

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