The finding of a cytoplasmic staining during antinuclear antibodies screening by indirect immunofluorescence on HEp-2 cells is not unusual. Some of these patterns, suggesting particularly autoantibodies directed against actine, mitochondria, ribosomes, aminoacyl-ARNt synthetases or SRP (signal recognition particle) need further examination, first of all by indirect immuno-fluorescence on rodent tissue sections. Others are self-sufficient; such a case is given by anti-Golgi antibodies. And finally, sometimes an unusual pattern in localisation or appearance of the fluorescent labelling will lead to the discovery of a monoclonal component. © 2006 Éditions scientifiques et médicales Elsevier SAS Tous droits réservés 0.
CITATION STYLE
Renier, G., & Beauvillain, C. (2006). Editorial. Revue Francophone Des Laboratoires, 2006(384), 43–50. https://doi.org/10.1016/S1773-035X(06)80303-5
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