Hydrogels are one of the upcoming classes of polymer-based controlled-release drug delivery systems. Besides exhibiting swelling-controlled drug release, hydrogels also show stimuli-responsive changes in their structural network and hence, the drug release. Because of large variations in physiological pH at various body sites in normal as well as pathological conditions, pH-responsive polymeric networks have been extensively studied. This review highlights the use of hydrogels (a class of polymeric systems) in controlled drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release.
CITATION STYLE
Gupta, P., Vermani, K., & Garg, S. (2002, May 15). Hydrogels: From controlled release to pH-responsive drug delivery. Drug Discovery Today. https://doi.org/10.1016/S1359-6446(02)02255-9
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