The neurobiology of sleep is introduced in the context of interacting wake and sleep systems. Specifically, the transitions from wake to sleep and from non-rapid eye movement to rapid eye movement sleep are discussed based on the flip-flop switch hypothesis. Regulation of wake and sleep according to the opposing homeostatic and circadian systems are also presented. © 2010 Elsevier Inc.
CITATION STYLE
Lu, B. S., & Zee, P. C. (2010, June). Neurobiology of sleep. Clinics in Chest Medicine. https://doi.org/10.1016/j.ccm.2010.02.004
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