The paced auditory serial addition test (PASAT) is increasingly used in multiple sclerosis (MS) studies. Since these studies rely on repeated assessments with relatively short inter-test intervals, practice effects can be a confounding factor. We examined intra-session PASAT practice effects in 70 relapsing remitting (RR) and 40 secondary progressive (SP) patients. The average number of correct answers increased from 39.6 ± 11.7 in the first PASAT run to 43.8 ± 11.4 in the second run for the RR group, and from 39.1 ± 11.6 to 41.8 ± 13.3 in the SP group. PASAT scores showed a consistent decrease when comparing the second half of each test to the first half for both patient groups, and for both runs. Items for which the answer was a number greater than 9 had the same discrimination ability as other test items, but were significantly more difficult. A simulation of 'single-button' responses supported the use of the simplified scoring method which is currently used in fMRI studies. Our results demonstrate a within-session PASAT practice effect in MS, as well as a fatigability effect for both patient groups. © 2008 SAGE Publications.
CITATION STYLE
Nagels, G., D’Hooghe, M. B., Kos, D., Engelborghs, S., & De Deyn, P. P. (2008). Within-session practice effect on paced auditory serial addition test in multiple sclerosis. Multiple Sclerosis, 14(1), 106–111. https://doi.org/10.1177/1352458507080062
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