Synthesis and biological evaluation of 4-thiazolidinone derivatives as antitubercular and antimicrobial agents

14Citations
Citations of this article
35Readers
Mendeley users who have this article in their library.

Abstract

New series of N-[2-{2-(substitutedphenyl)-4-oxo-5-(substitutedbenzylidene)-1,3-thiazolidine}-iminoethyl]-2-amino-5-nitrothiazole, 5(a-m) have been synthesized from 2-amino-5-nitrothiazole as a starting material by conventional as well as microwave methods. All the synthesized compounds 4(a-m) were screened for their antibacterial and antifungal activities against some selected bacteria and fungi and antitubercular activity screened against Mycobacterium tuberculosis. The structure of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR, 1H NMR, 13C NMR and FAB-Mass.

Cite

CITATION STYLE

APA

Samadhiya, P., Sharma, R., Srivastava, S. K., & Srivastava, S. D. (2014). Synthesis and biological evaluation of 4-thiazolidinone derivatives as antitubercular and antimicrobial agents. Arabian Journal of Chemistry, 7(5), 657–665. https://doi.org/10.1016/j.arabjc.2010.11.015

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free