Abstract
Radiation-induced DNA damage and related repair mechanisms are described in this chapter. The emerging connection with growth factor induced signal transduction is described, with important implications for radiotherapy. The prospect of developing targeting agents, which selectively deliver radioactivity to the tumor and at the same time radiosensitize the tumor cells is discussed in some detail. © 2008 Springer Science+Business Media B.V.
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CITATION STYLE
Stenerlöw, B., Ekerljung, L., Carlsson, J., & Lennartsson, J. (2008). Radiation induced DNA-damage/repair and associated signaling pathways. In Targeted Radionuclide Tumor Therapy: Biological Aspects (pp. 249–266). Springer Netherlands. https://doi.org/10.1007/978-1-4020-8696-0_13
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