Upper extremity deep vein thrombosis: Pathogenesis and treatment

Abstract

Upper extremity deep vein thrombosis (UEDVT) may be the first manifestation of venous thoracic outlet syndrome (VTOS). It primarily affects young, physically active people. The clinical findings depend on the degree of obstruction of the subclavian vein. Correct diagnosis — aided by various imaging modalities — as well as rapid initiation of local thrombolytic therapy, surgical decompression of the thoracic outlet (when indications are present), and the immediate initiation of anticoagulation therapy aim at successfully restoring the patient’s quality of life.