Nanoparticles for Radionuclide Imaging and Therapy: Principles

Abstract

Nanoparticles for radionuclide imaging and therapy have been deeply investigated the last ten years. According to their chemical composition, five families can be distinguished, including metal, carbon, polymers, and lipid- and nucleolipid-based nanoparticles. These nanoparticles were radiolabeled using mainly two strategies: (i) labeling of the nanostructure itself or (ii) labeling of the payload encapsulated inside the nanoparticles. This chapter will highlight recent contributions in this field.