Markers of inflammation: Data from the MOSAIC randomised trial of CPAP for minimally symptomatic OSA

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Abstract

The Multi-centre Obstructive Sleep Apnoea Interventional Cardiovascular (MOSAIC) trial compared 6 months of CPAP therapy, versus no CPAP, in 391 patients with minimally symptomatic obstructive sleep apnoea (OSA). We now report some exploratory outcomes, markers of systemic inflammation (interleukin 6 (IL-6), IL-10, C reactive protein, tumour necrosis factor). We found no consistent changes (all p values >0.13).

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Stradling, J. R., Craig, S. E., Kohler, M., Nicoll, D., Ayers, L., Nunn, A. J., & Bratton, D. J. (2015). Markers of inflammation: Data from the MOSAIC randomised trial of CPAP for minimally symptomatic OSA. Thorax, 70(2), 181–182. https://doi.org/10.1136/thoraxjnl-2014-205958

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