A 12-year-old mixed breed dog was evaluated for marked hypercalcemia that was identified during assessment for acute polydipsia and polyuria. Physical examination identified a new grade II/VI left apical systolic murmur. A mass involving the left ventricular posterior wall and left atrium was identified by echocardiography, suggesting neoplastic invasion into the myocardium. The patient was euthanized, and post-mortem cardiac evaluation identified an intramyocardial amyloid-producing plasma cell tumor. Multiple myeloma was suspected but could not be confirmed due to the limited post-mortem evaluation. This case is the first report of myocardial amyloidosis in a dog with a myeloma-related disorder (MRD). Dogs with MRD and myocardial involvement may not exhibit clinical signs that localize to the cardiovascular system; therefore, echocardiography should be considered during the staging process.
CITATION STYLE
Alessandrino, K., Tjostheim, S. S., Flynn, K. M., Cole, C., & Aschenbroich, S. (2023). Myocardial plasma cell tumor with intratumoral amyloidosis in a dog. Journal of Veterinary Cardiology, 50, 23–28. https://doi.org/10.1016/j.jvc.2023.09.004
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