The Kounis-Zavras Syndrome with the Samter-Beer Triad

  • Schwartz B
  • Daulat S
  • Kuiper J
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Abstract

We present a case of Kounis-Zavras syndrome in the setting of aspirin-induced asthma, or the Samter-Beer triad of asthma, nasal polyps, and aspirin allergy. The Kounis-Zavras syndrome, also known as Kounis syndrome, leads to angina pectoris or acute coronary syndrome secondary to coronary vasospasm in response to an allergic stimulus, leading to mast-cell degranulation of vasospastic mediators. The vasospasm can result in myocardial infarction, as it did in our patient.

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Schwartz, B. G., Daulat, S., & Kuiper, J. (2011). The Kounis-Zavras Syndrome with the Samter-Beer Triad. Baylor University Medical Center Proceedings, 24(2), 107–109. https://doi.org/10.1080/08998280.2011.11928695

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