Seguimiento de las recomendaciones sobre psicofarmacología y su repercusión conductual en la discapacidad intelectual

Abstract

Subjects with Intellectual Disability (ID) are frequently affected by behavioral and psychiatric co-mobility. As a consequence between 1/3 and 3/4 are under antipsychotic treatment. It is available an expert consensus guideline with the purpose of guiding pharmacological treatment decisions. The achievement of expert recommendations may optimize drug therapy efficacy and reduce behavioral problems as well as enhance adaptive abilities. The "Inventory for client and agency planning" (ICAP) is a psychometric tool designed to assess health care to ID patients, and includes items that grade behavioral and adaptive problems. We designed a transversal study in order to determine the association between the follow-up of expert recommendations and the scores achieved on behavioral and adaptive problems items. Drug therapy been prescribed to patients diagnosed of ID (CIE-10) was analyzed and classified into a dichotomous "Do" or "Do not" achieve guideline recommendations in regard of several pharmaceutical aspects such as drug therapy indication, dosage, treatment duration and poly-pharmacy. Scores from ICAP tool as compared to guideline compliance. Follow-up of dose criteria was associated to a better adaptive behavior (p<0,05) and follow-up of poly-pharmacy criteria and duration treatment criteria was associated better behavioral out comes (p<0,05). We found no association between follow-up of indication criteria and behavioral or adaptive problems.