Mining Human Microbiome for Therapeutics

Abstract

Human microbiome is known to play a key role in human health along with the host genetic makeup and environmental factors. Research studies carried out in the past decade have now established a clear association of human microbiome with various metabolic and gastrointestinal diseases through the state of dysbiosis. Extensive efforts have been made to develop novel and effective methods such as the use of probiotics and fecal microbiota transplantation (FMT) as corrective measures to improve the human health. It is indeed now important to understand the concepts and developmental process of such alternative biotherapeutics to develop potential treatment regimens. This chapter gives insights into the history, development, and the current scenario of the use of these techniques. The process of how these techniques have been developed through mining of the human microbiome is discussed broadly.