Although clinical requests for D-dimer are generally in the minority of assays in the routine clinical laboratory, they are an important aspect - especially if the laboratory supports an active emergency room and hematology service. Throughout the literature, D-dimer assays have been used for many purposes in the research setting; however it is generally the negative predictive value of the assay that is the most common piece of information being utilized from the standpoint of a clinician. Research or clinical needs will dictate the type of assay required - a qualitative, semiquantitative, or quantitative D-dimer assay may be appropriate for a particular purpose. Commonalities and differences between these assay types are outlined here, as well as universal concerns regarding standardization of D-dimer assay results. © 2013 Springer Science+Business Media New York.
CITATION STYLE
Stang, L. J. (2013). D-dimer and fibrinogen/fibrin degradation products. Methods in Molecular Biology, 992, 415–427. https://doi.org/10.1007/978-1-62703-339-8_34
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