Graviola in Metastatic Ovarian Cancer: A Case Report of Sustained Disease Stability

Abstract

Treatments for metastatic ovarian cancer to date have been limited by advanced stages at diagnosis, drug toxicity and resistance. Cancer patients are also increasingly looking towards complementary and alternative therapies. Graviola (Annona muricata) has traditionally been used in many conditions including cancer, and both in vivo and in vitro studies have shown evidence of anti-cancer effects. We present a case of a patient with metastatic ovarian cancer who progressed through multiple lines of chemotherapy but had a response and sustained stability in Ca-125 levels whilst taking graviola tablets. Further clinical research is warranted to evaluate graviola’s role in cancer therapy.