Three pseudomonas putida FNR family proteins with different sensitivities to O2

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Abstract

Background: FNR proteins are O2-responsive bacterial transcription factors. Results: Pseudomonas putida possesses three FNR proteins with iron-sulfur clusters that have different sensitivities to O2. Conclusion: The mechanism of the iron-sulfur cluster reaction with O2 is conserved among FNR proteins. Significance: Differential sensitivity of multiple FNR proteins extends the range of O2-responsive gene expression within a single bacterium.

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Ibrahim, S. A., Crack, J. C., Rolfe, M. D., Borrero-De Acuña, J. M., Thomson, A. J., Le Brun, N. E., … Green, J. (2015). Three pseudomonas putida FNR family proteins with different sensitivities to O2. Journal of Biological Chemistry, 290(27), 16812–16823. https://doi.org/10.1074/jbc.M115.654079

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