The Challenges of Producing Bilayer Tablet: A Review

Abstract

Bilayer tablets are the advanced form of conventional immediate release tablet system, which consist of either two similar or different drugs combined in a single dose for effective treatment of the disease improving patient compliance. However, the multilayer tablet technology is demanding It also necessitates meticulous selection of excipients and manufacturing conditions for each technological stage. The aim of this review is to provide an outline of state of art of bilayer tablet technology and emphasise the difficulties experienced during Bilayer tablet manufacturing along with its  intend solutions for these challenges. Keyword: Bilayer tablet, Conventional release, Challenges encountered, Compliance.