Complementary to other imaging techniques, MALDI MS imaging provides label-free analysis and chemical specificity, covering a wide range of molecules that can be visualized simultaneously. Here, we highlight a protocol to visualize lipids from single cardiac cells using high-resolution atmospheric-pressure matrix-assisted laser desorption/ionization coupled to an orbital trapping mass analyzer.
CITATION STYLE
Bhandari, D. R., Coliva, G., Fedorova, M., & Spengler, B. (2020). Single cell analysis by high-resolution atmospheric-pressure MALDI MS imaging. In Methods in Molecular Biology (Vol. 2064, pp. 103–111). Humana Press Inc. https://doi.org/10.1007/978-1-4939-9831-9_8
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